LectureNotesinBioinformatics4316EditedbyS.Istrail,P.Pevzner,andM.WatermanEditorialBoard:A.ApostolicoS.BrunakM.GelfandT.LengauerS.MiyanoG.MyersM.-F.SagotD.SankoffR.ShamirT.SpeedM.VingronW.WongSubseriesofLectureNotesinComputerScience