A novel full duplex wavelength division multiplexing radio over fiber WDM RoF system based on optical frequency comb OFC which can generate dual frequency microwave signal simultaneously and realize wavelength reuse for uplink transmission is proposed.In this proposal OFC which serves as the optical carriers of the WDM RoF network is performed by cascading two electro absorption modulators EAMs and a frequency modulator FM.The optical carriers are modulated by the radio frequency.